Wednesday, August 15, 2012
ECHA Publishes Practical Guide for Reporting Toxicity Data for REACH
The most critical part of the guide explains how to undertake the take of "Derivation of No Effect Levels" (DNELs), which are used to compare toxicity to exposure in the assessment of risk. DNELs must be derived for all relevant toxicological endpoints (e.g., oral and dermal exposures) and represent the effects side of the equation for human health concerns. For environmental concerns there is a similar derivation of "Predicted No Effect Levels" (PNECs) for aquatic and terrestrial organisms. PNEC derivation is not discussed in the new practical guide.
More information on the Practical Guide can be found on the ECHA web site.
The Practical Guide in PDF format can be downloaded directly here.